Preclinical services for determination of the efficacy of drug or drug candidates:

  • hot-plate (stable and increasing temperature)
  • migrain headache (meningeal blood flow and neurogenic inflammation)
  • In vivo electrophysiology (rat, rabbit, zebrafish)
  • In vivo haemodynamics (rat, guinea pig, mice, rabbit)
  • whole body insulin sensitivity (rapid insulimn sensitivity test, hyperinsulinaemic euglycaemic glucose clamping, HOMA indices)
  • hepatic glucose production, peripheral glucose uptake

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